Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 7/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 7/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316623 | 0.90 | P2RX3 (0.39) | ALKBH1GRM5ALDH1A1KDM4ERXRA | |
| SCHEMBL24316428 | 0.88 | ALKBH1 (0.39) | ALKBH1PDE1APDE1BPDE1CGRM5 | |
| SCHEMBL24316545 | 0.86 | CSF1R (0.43) | ALKBH1PDE1APDE1BPDE1CGRM5 | |
| SCHEMBL24316434 | 0.85 | CSF1R (0.53) | ALKBH1PDE1APDE1BPDE1CGRM5 | |
| SCHEMBL24316565 | 0.84 | CSF1R (0.44) | ALKBH1PDE1APDE1BPDE1CGRM5 | |
| SCHEMBL24316660 | 0.81 | CSF1R (0.40) | ALKBH1GRM5ALDH1A1KDM4EPKM | |
| SCHEMBL24316658 | 0.80 | CSF1R (0.42) | ALKBH1PDE1APDE1BPDE1CGRM5 | |
| SCHEMBL24316982 | 0.80 | CSF1R (0.48) | ALKBH1GRM5ALDH1A1KDM4EPKM | |
| SCHEMBL24316436 | 0.80 | KDM4E (0.37) | GRM5ALDH1A1KDM4EUSP2CYP1A2 | |
| SCHEMBL24316432 | 0.79 | ACACB (0.37) | ALKBH1GRM5ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |