Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316659 | 0.90 | ALKBH1 (0.40) | ALDH1A1ALKBH1KDM4ENPC1RAB9A | |
| SCHEMBL24316814 | 0.83 | CSF1R (0.47) | P2RX3ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL24316428 | 0.79 | ALKBH1 (0.39) | ALDH1A1ALKBH1KDM4ENPC1RAB9A | |
| SCHEMBL24316432 | 0.78 | ACACB (0.37) | ALDH1A1ALKBH1GRM5MCHR1USP2 | |
| SCHEMBL24316438 | 0.77 | GRM5 (0.43) | P2RX3GRM5 | |
| SCHEMBL24316545 | 0.77 | CSF1R (0.43) | ALDH1A1ALKBH1KDM4ENPC1RAB9A | |
| SCHEMBL24316448 | 0.76 | CSF1R (0.45) | GRM5MCHR1MAOBMAOAACHE | |
| SCHEMBL24316434 | 0.76 | CSF1R (0.53) | ALDH1A1ALKBH1KDM4ENPC1RAB9A | |
| SCHEMBL24316565 | 0.75 | CSF1R (0.44) | ALDH1A1ALKBH1KDM4ENPC1RAB9A | |
| SCHEMBL24316624 | 0.73 | KDM4E (0.36) | ALDH1A1KDM4EGRM5MCHR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |