Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26942017 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTADRB3ADRB1ADRB2 | |
| SCHEMBL24328906 | 0.85 | HTR6 (0.42) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL24328921 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL28417401 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL24328928 | 0.80 | MTNR1A (0.58) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL28417399 | 0.80 | MTNR1A (0.58) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL28416704 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL30024220 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTAPAF1POLB | |
| SCHEMBL24301152 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2MPO | |
| SCHEMBL24328355 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EMAPTAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | SMN1; SMN2 3812/4885KDM4E 1022/4885MAPT 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.