Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328930 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTMPOMAPTADRB1 | |
| SCHEMBL26941996 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2HTR6SLC6A4MTNR1AMTNR1B | |
| SCHEMBL24328906 | 0.78 | HTR6 (0.42) | SMN1; SMN2HTTMPOHTR6MTNR1A | |
| SCHEMBL28417401 | 0.69 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTMPOHTR2AMAPT | |
| SCHEMBL24328921 | 0.69 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTMPOHTR2AMAPT | |
| SCHEMBL24328929 | 0.69 | SMN1; SMN2 (0.57) | SMN1; SMN2MPOHTR6HTR2AHTR1A | |
| SCHEMBL28417399 | 0.68 | MTNR1A (0.58) | SMN1; SMN2HTTHTR6MTNR1AMTNR1B | |
| SCHEMBL24328928 | 0.68 | MTNR1A (0.58) | SMN1; SMN2HTTHTR6MTNR1AMTNR1B | |
| SCHEMBL31177153 | 0.67 | PTGS2 (0.69) | MTNR1AMTNR1BCDK4CCND1 | |
| SCHEMBL24301152 | 0.67 | SMN1; SMN2 (0.61) | SMN1; SMN2MPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | SMN1; SMN2 3812/4885HTT 362/4885MPO 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.