SCHEMBL24329187

SCHEMBL24329187

CN1C(=O)C(=C2CC(c3ccc(Oc4ccccc4)cc3)NN2)C(=O)N(C)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.38
SCN3A Q9NY46 1/20 0.38
FFAR1 O14842 3/20 0.37
GRIA2 P42262 1/20 0.36
ABCB1 P08183 2/20 0.35
GSTP1 P09211 1/20 0.35
THRB P10828 1/20 0.35
KDM1A O60341 1/20 0.34
BRD4 O60885 1/20 0.34
LMNA P02545 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H4 Q96RI1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24328743 0.89 BRD4 (0.42) BRD4LMNAALDH1A1MAPTHPGD
SCHEMBL24329754 0.88 BRD4 (0.42) BRD4KMT2ACHRNA7
SCHEMBL24329099 0.86 KMT2A (0.40) THRBLMNAALDH1A1MAPTKMT2A
SCHEMBL29564321 0.82 TP53 (0.34) BRD4LMNAALDH1A1MAPTKMT2A
SCHEMBL24328744 0.82 MEN1 (0.39) KCNH2ALDH1A1HPGDKMT2A
SCHEMBL29565262 0.81 ALDH1A1 (0.36) THRBBRD4LMNAALDH1A1MAPT
SCHEMBL29564756 0.81 TDP1 (0.32) LMNAKMT2ATDP1
SCHEMBL24329761 0.74 FFAR1 (0.38) KCNH2SCN3AFFAR1ABCB1MMP2
SCHEMBL24329755 0.74
SCHEMBL24329665 0.70 BRD4 (0.40) BRD4ALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022080346-A1 NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF 国立大学法人佐賀大学 2022-04-21 WO disclosed
WO-2022080346-A1 NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF 国立大学法人佐賀大学 2022-04-21 WO disclosed