Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564756 | 0.88 | TDP1 (0.32) | ATMMEN1LMNAKMT2AGAA | |
| SCHEMBL29565262 | 0.88 | ALDH1A1 (0.36) | MAPTPTGS2NPSR1ALDH1A1MEN1 | |
| SCHEMBL24328743 | 0.87 | BRD4 (0.42) | MAPTALDH1A1ATMMEN1LMNA | |
| SCHEMBL24329754 | 0.86 | BRD4 (0.42) | PTGS2KMT2AKDM4EBRD4 | |
| SCHEMBL24329099 | 0.85 | KMT2A (0.40) | TP53MAPTPTGS2APPALDH1A1 | |
| SCHEMBL24329187 | 0.82 | KCNH2 (0.38) | MAPTNPSR1ALDH1A1LMNAKMT2A | |
| SCHEMBL24328744 | 0.81 | MEN1 (0.39) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24329755 | 0.80 | — | — | |
| SCHEMBL10228790 | 0.72 | MAPT (0.39) | MAPTGFERNPSR1ALDH1A1ATM | |
| SCHEMBL24329162 | 0.70 | MAOA (0.39) | TP53PTGS2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080346-A1 | NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF | 国立大学法人佐賀大学 | 2022-04-21 | — | — | WO | disclosed |