Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328743 | 0.93 | BRD4 (0.42) | BRD4HSD17B2TSHRKMT2AKDM4E | |
| SCHEMBL24329187 | 0.88 | KCNH2 (0.38) | BRD4KMT2ACHRNA7 | |
| SCHEMBL29564321 | 0.86 | TP53 (0.34) | BRD4PTGS2KMT2AKDM4E | |
| SCHEMBL29564756 | 0.85 | TDP1 (0.32) | HSD17B2TSHRKMT2ABACE1MAOB | |
| SCHEMBL29565262 | 0.85 | ALDH1A1 (0.36) | BRD4HSD17B2PTGS2TSHRKMT2A | |
| SCHEMBL24328744 | 0.84 | MEN1 (0.39) | KMT2AKDM4E | |
| SCHEMBL24329099 | 0.83 | KMT2A (0.40) | NR1H2NR1H3PTGS2KMT2AKDM4E | |
| SCHEMBL24329755 | 0.80 | — | — | |
| SCHEMBL24329665 | 0.73 | BRD4 (0.40) | BRD4HSD17B2TSHRKMT2AKDM4E | |
| SCHEMBL24328749 | 0.72 | NPSR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080346-A1 | NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF | 国立大学法人佐賀大学 | 2022-04-21 | — | — | WO | disclosed |
| WO-2022080346-A1 | NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF | 国立大学法人佐賀大学 | 2022-04-21 | — | — | WO | disclosed |