Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 11/20 | 0.32 |
| ▸ | FEN1 | P39748 | 11/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469622 | 0.84 | KMT2A (0.33) | ALOX5APFEN1ALDH1A1GAAMAPT | |
| SCHEMBL24334438 | 0.77 | SLC22A12 (0.36) | ALDH1A1GAAMAPTGFERKMT2A | |
| SCHEMBL24333964 | 0.77 | HTR6 (0.33) | ALDH1A1GAAMAPTGFERKMT2A | |
| SCHEMBL24334248 | 0.76 | ALDH1A1 (0.32) | ALDH1A1GAAMAPTGFERKMT2A | |
| SCHEMBL24333670 | 0.76 | CCR8 (0.33) | ALDH1A1GAAMAPTGFERKMT2A | |
| SCHEMBL24334285 | 0.75 | NPC1 (0.33) | ALDH1A1MAPTKMT2A | |
| SCHEMBL24333377 | 0.72 | LMNA (0.34) | ALDH1A1MAPTKMT2A | |
| SCHEMBL24333658 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTKMT2A | |
| SCHEMBL24334394 | 0.72 | PGAM1 (0.33) | ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL24334224 | 0.72 | NFE2L2 (0.35) | ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |