SCHEMBL24376718

SCHEMBL24376718

CCCCCCCC(CCCCC)C1=C(O)COC1=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.42
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36
PSENEN Q9NZ42 1/20 0.36
GPR84 Q9NQS5 3/20 0.33
FDPS P14324 3/20 0.33
PDCD4 Q53EL6 1/20 0.33
PTPN1 P18031 1/20 0.33
ACP1 P24666 1/20 0.33
CDC25B P30305 1/20 0.33
NQO1 P15559 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7481386 0.92 DUSP3 (0.38) DUSP3PSEN1PSEN2APH1BNCSTN
SCHEMBL24376277 0.71 PSEN1 (0.35) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL24376835 0.70 PTPN1 (0.39) GPR84FDPSPTPN1FFAR1
SCHEMBL24849580 0.66 PDCD4 (0.39) DUSP3GPR84FDPSPDCD4FFAR1
SCHEMBL6253781 0.63 GPR84 (0.38) DUSP3GPR84FDPSFFAR1
SCHEMBL19374387 0.63 GPR84 (0.40) GPR84FDPSFFAR1
SCHEMBL9631580 0.62 LMNA (0.35) GPR84
SCHEMBL3462845 0.62 LMNA (0.35) GPR84
SCHEMBL23545051 0.62 CA2 (0.39) GPR84FDPSNQO1FFAR1
SCHEMBL24450057 0.62 CA2 (0.39) GPR84FDPSNQO1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127255-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (GB) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127255-A1 HERBICIDAL COMPOUNDS DDT, HDHD5, HPD DUSP3 993/4885PSEN1 3482/4885PSEN2 3939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.