SCHEMBL24376835

SCHEMBL24376835

CCCCCCC(CCCCC)C1=C(O)CN(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GBA1 P04062 1/20 0.34
ACE P12821 3/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GPR84 Q9NQS5 3/20 0.33
FDPS P14324 3/20 0.33
FFAR1 O14842 1/20 0.33
PRKCD Q05655 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24376718 0.70 DUSP3 (0.42) PTPN1GPR84FDPSFFAR1
SCHEMBL24376277 0.70 PSEN1 (0.35) LMNAGPR84FDPSFFAR1
SCHEMBL7481386 0.62 DUSP3 (0.38) PTPN1
SCHEMBL24450057 0.61 CA2 (0.39) LMNAGPR84FDPSFFAR1
SCHEMBL29004050 0.61 TRPA1 (0.38) PTPN1GBA1ACEGPR84FDPS
SCHEMBL23545051 0.61 CA2 (0.39) LMNAGPR84FDPSFFAR1
SCHEMBL23509686 0.59 RGS4 (0.44) PTPN1LMNASMN1; SMN2HTTALDH1A1
SCHEMBL4062741 0.57 TSHR (0.57) LMNAGPR84FDPSFFAR1
SCHEMBL634579 0.57 TSHR (0.57) LMNAGPR84FDPSFFAR1
SCHEMBL14533500 0.57 TSHR (0.57) LMNAGPR84FDPSFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127255-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (GB) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127255-A1 HERBICIDAL COMPOUNDS DDT, HDHD5, HPD PTPN1 440/4885LMNA 4081/4885SMN1; SMN2 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.