SCHEMBL24378348

SCHEMBL24378348

CC(C)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.71
CTSS P25774 1/20 0.71
CTSK P43235 1/20 0.71
MAPT P10636 3/20 0.70
TP53 P04637 1/20 0.70
TACR1 P25103 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.65
ACE P12821 2/20 0.64
SSTR3 P32745 1/20 0.60
SCN9A Q15858 1/20 0.58
POLB P06746 1/20 0.58
P4HB P07237 1/20 0.58
CCKBR P32239 2/20 0.57
REN P00797 1/20 0.57
KLK7 P49862 1/20 0.56
TACR3 P29371 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849843 0.90 CTSL (0.72) CTSLCTSSCTSKMAPTTP53
SCHEMBL850438 0.90 ACE (0.77) CTSLCTSSCTSKMAPTTP53
SCHEMBL12267036 0.90 CTSL (0.72) CTSLCTSSCTSKMAPTTP53
SCHEMBL30976323 0.90 ACE (0.77) CTSLCTSSCTSKMAPTTP53
SCHEMBL1486167 0.90 ACE (0.77) CTSLCTSSCTSKMAPTTP53
SCHEMBL29367687 0.90 ACE (0.77) CTSLCTSSCTSKMAPTTP53
SCHEMBL1003555 0.90 ACE (0.77) CTSLCTSSCTSKMAPTTP53
SCHEMBL5251038 0.89 TACR1 (0.78) CTSLCTSSCTSKMAPTTP53
SCHEMBL20328577 0.89 CTSL (0.71) CTSLCTSSCTSKMAPTTP53
SCHEMBL7413708 0.89 CTSL (0.71) CTSLCTSSCTSKMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127239-A1 GLYCOSYL DONOR, PREPARATION METHOD THEREFOR, AND USE THEREOF SICHUAN UNIVERSITY (CN) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127239-A1 GLYCOSYL DONOR, PREPARATION METHOD THEREFOR, AND USE THEREOF UGGT1, ALG8, FUT6 CTSL 627/4885CTSS 1621/4885CTSK 1955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.