Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378840 | 0.80 | WNT1 (0.34) | CYP1A2CYP2D6ALOX15CARM1PRMT6 | |
| SCHEMBL29326374 | 0.79 | ALOX15 (0.45) | KDM1AHSD11B1KDM4EALDH1A1SLC18A3 | |
| SCHEMBL15986991 | 0.77 | ALOX15 (0.46) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL24378839 | 0.77 | HSD11B1 (0.42) | KDM1AHSD11B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL15100017 | 0.77 | TSHR (0.40) | HSD11B1KDM4ESMN1; SMN2 | |
| SCHEMBL24378832 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1CYP1A2CYP2D6ALOX15 | |
| SCHEMBL25923906 | 0.74 | KDM1A (0.46) | KDM1AHSD11B1KDM4EALDH1A1SLC18A3 | |
| SCHEMBL18820471 | 0.73 | KDM4E (0.42) | KDM1AHSD11B1KDM4EALDH1A1SLC18A3 | |
| SCHEMBL14414891 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL22629445 | 0.73 | SIGMAR1 (0.43) | CYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083616-A1 | QUINAZOLINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 贝达药业股份有限公司 | 2022-04-28 | — | — | WO | disclosed |