Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378833 | 0.80 | KDM1A (0.39) | CYP1A2CYP2D6ALOX15CARM1PRMT6 | |
| SCHEMBL24378839 | 0.77 | HSD11B1 (0.42) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL15986991 | 0.77 | ALOX15 (0.46) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL25001374 | 0.77 | OPRM1 (0.35) | OPRM1OPRD1OPRK1CYP1A2CYP2D6 | |
| SCHEMBL15100017 | 0.77 | TSHR (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL24378832 | 0.76 | ALDH1A1 (0.52) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL23741032 | 0.76 | WNT1 (0.33) | WNT1GSK3BDYRK1AOPRM1OPRD1 | |
| SCHEMBL14414891 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL22629445 | 0.73 | SIGMAR1 (0.43) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL24480556 | 0.72 | ACHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083616-A1 | QUINAZOLINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 贝达药业股份有限公司 | 2022-04-28 | — | — | WO | disclosed |