Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12543290 | 0.91 | ALDH1A1 (0.44) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL12543781 | 0.85 | RAB9A (0.43) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17361120 | 0.78 | HSD11B1 (0.39) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL24399484 | 0.78 | ALDH1A1 (0.42) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL22911797 | 0.74 | LMNA (0.43) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1958682 | 0.74 | RAB9A (0.42) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20987918 | 0.73 | MMP2 (0.35) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL1962214 | 0.72 | ALDH1A1 (0.36) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL23986656 | 0.72 | ALDH1A1 (0.66) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL12543265 | 0.71 | NPC1 (0.46) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094271-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |