Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303573 | 0.84 | TSHR (0.53) | L3MBTL1FABP4MAPTALDH1A1TSHR | |
| SCHEMBL3642110 | 0.82 | ALDH1A1 (0.59) | MAPTALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL9633696 | 0.81 | SMN1; SMN2 (0.60) | L3MBTL1MAPTALDH1A1GLAGAA | |
| SCHEMBL9632487 | 0.79 | L3MBTL1 (0.62) | L3MBTL1MAPTALDH1A1GLAUSP2 | |
| SCHEMBL30997420 | 0.77 | CA5A (0.47) | L3MBTL1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL30610782 | 0.77 | PKM (0.57) | L3MBTL1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL4660848 | 0.77 | CA5A (0.47) | L3MBTL1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL48765 | 0.77 | PKM (0.57) | L3MBTL1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL29265076 | 0.77 | MAPT (0.49) | L3MBTL1MAPTALDH1A1GLAUSP2 | |
| SCHEMBL9634049 | 0.77 | POLB (0.60) | L3MBTL1MAPTALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | PI4KB, PI4KA, PI4K2A | L3MBTL1 331/4885FABP4 3106/4885TNF 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.