Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632487 | 0.93 | L3MBTL1 (0.62) | POLBALDH1A1L3MBTL1L3MBTL3MAPT | |
| SCHEMBL9633696 | 0.87 | SMN1; SMN2 (0.60) | POLBALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL29265076 | 0.85 | MAPT (0.49) | POLBALDH1A1L3MBTL1MAPTPKM | |
| SCHEMBL20314704 | 0.79 | L3MBTL3 (0.74) | POLBALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24435822 | 0.77 | L3MBTL1 (0.62) | ALDH1A1CYP3A4L3MBTL1MAPTLMNA | |
| SCHEMBL48765 | 0.76 | PKM (0.57) | ALDH1A1CYP3A4L3MBTL1MAPTHTT | |
| SCHEMBL30997420 | 0.76 | CA5A (0.47) | POLBALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL30610782 | 0.76 | PKM (0.57) | ALDH1A1CYP3A4L3MBTL1MAPTHTT | |
| SCHEMBL4660848 | 0.76 | CA5A (0.47) | POLBALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL13185619 | 0.76 | ALPL (0.56) | POLBALDH1A1L3MBTL1L3MBTL3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |