Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493286 | 0.90 | GPR119 (0.48) | GPR119CETPFAAH | |
| SCHEMBL24493212 | 0.81 | GPR119 (0.48) | GPR119FAAH | |
| SCHEMBL24493084 | 0.78 | ACHE (0.40) | — | |
| SCHEMBL24493082 | 0.77 | ACHE (0.41) | — | |
| SCHEMBL15939449 | 0.77 | GPR119 (0.46) | GPR119P2RX7FAAH | |
| SCHEMBL29079551 | 0.75 | GPR119 (0.46) | GPR119P2RX7FAAH | |
| SCHEMBL25269372 | 0.75 | P2RX7 (0.47) | GPR119P2RX7FAAH | |
| SCHEMBL16012151 | 0.72 | FAAH (0.50) | GPR119FAAH | |
| SCHEMBL22719074 | 0.71 | DDB1 (0.53) | GPR119 | |
| SCHEMBL26229010 | 0.71 | DDB1 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255900-A2 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022118016-A2 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-06-09 | — | — | WO | disclosed |