Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59858 | 0.93 | TGM2 (0.55) | TGM2GAAKMT2ALMNAHPGD | |
| SCHEMBL410698 | 0.82 | TSHR (0.52) | TGM2GAAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL647494 | 0.81 | MEN1 (0.57) | TGM2KMT2AALDH1A1TDP1 | |
| SCHEMBL8764868 | 0.81 | KMT2A (0.47) | TGM2GAAKMT2ALMNARAB9A | |
| SCHEMBL5082541 | 0.81 | KMT2A (0.67) | TGM2GAAKMT2ALMNAHPGD | |
| SCHEMBL8765327 | 0.81 | NPC1 (0.66) | KMT2AL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL15938100 | 0.81 | ALDH1A1 (0.49) | TGM2GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL40744 | 0.79 | TGM2 (0.68) | TGM2GAAKMT2ALMNAHPGD | |
| SCHEMBL7838836 | 0.79 | HTT (0.49) | TGM2GAAKMT2ALMNAHPGD | |
| SCHEMBL9185736 | 0.79 | TGM2 (0.46) | TGM2GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547688-B1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8623934-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8541483-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130178594-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-8415405-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2547688-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | Johnson & Johnson Vision Care, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. | 2011-09-29 | — | — | US | disclosed |
| WO-2011116206-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-20080177002-A1 | Thermoplastic Resin Composition, Optical Film, And Process For Producing Film | JSR CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| EP-1837374-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM, AND PROCESS FOR PRODUCING FILM | JSR Corporation (JP) | 2007-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | TGM2 1299/4885GAA 3874/4885KMT2A 853/4885 |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | TGM2 1299/4885GAA 3874/4885KMT2A 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.