Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.34 |
| ▸ | PGR | P06401 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523752 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1GAAMAPTIMPDH2 | |
| SCHEMBL24523731 | 0.77 | IMPDH2 (0.33) | KDM4EALDH1A1GAAMAPTIMPDH2 | |
| SCHEMBL24523770 | 0.75 | IMPDH2 (0.38) | KDM4EALDH1A1GAAMAPTIMPDH2 | |
| SCHEMBL24523744 | 0.75 | AR (0.44) | ARPGR | |
| SCHEMBL24523964 | 0.72 | PNMT (0.31) | KDM4EALDH1A1ELANEIMPDH2 | |
| SCHEMBL24524314 | 0.72 | PNMT (0.33) | ARKDM4EALDH1A1GAAMAPT | |
| SCHEMBL24524356 | 0.71 | KDM4E (0.33) | KDM4EALDH1A1IMPDH2 | |
| SCHEMBL24523742 | 0.71 | IMPDH2 (0.34) | KDM4EALDH1A1GAAMAPTIMPDH2 | |
| SCHEMBL24523750 | 0.71 | MAOA (0.40) | KDM4EALDH1A1GAAMAPTIMPDH2 | |
| SCHEMBL24523738 | 0.69 | TRPV4 (0.38) | KDM4EALDH1A1MAPTIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |