Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823063 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL36762 | 0.83 | HSD17B10 (1.00) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL29357214 | 0.83 | HSD17B10 (1.00) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL226196 | 0.83 | HSD17B10 (0.76) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL7356436 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL761745 | 0.81 | HSD17B10 (0.73) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL11660676 | 0.79 | HSD17B10 (0.70) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL3361843 | 0.79 | HSD17B10 (0.70) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL4473108 | 0.79 | HSD17B10 (0.70) | KDM4EALDH1A1GAAMAPTTAAR1 | |
| SCHEMBL4019720 | 0.79 | HSD17B10 (0.70) | KDM4EALDH1A1GAAMAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066682-A1 | Arylalkylamine vanadium (V) salts for the treatment and/or prevention of Diabetes mellitus | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | claimed |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
| CN-114349718-A | Preparation method of thiadiazole derivative drug intermediate containing amino alkyl naphthol structure | 南京苏亦欣医药科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-2657214-B1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | MITSUBISHI GAS CHEMICAL CO (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-8993774-B2 | Process for production of aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20130303775-A1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-2657214-A1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | Mitsubishi Gas Chemical Company, Inc. (JP) | 2013-10-30 | — | — | EP | disclosed |
| US-8013019-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC (US) | 2011-09-06 | — | — | US | disclosed |
| US-8013019-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC (US) | 2011-09-06 | — | — | US | disclosed |
| US-8013019-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC (US) | 2011-09-06 | — | — | US | disclosed |
| US-5852221-A | Optically active β-aminoalkoxyborane complex | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5808098-A | REDUCING AGENT FROM AMINOALCOHOL | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0680484-B1 | OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEXES | NISSAN CHEMICAL IND LTD (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5786485-A | REACTING OPTICALLY ACTIVE BETA-AMINOALCOHOL WITH BORANE REAGENT TO PRODUCE OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5767277-A | REDUCING AGENT FOR A CARBONYL COMPOUND TO PRODUCE A 1,3-SYN-DIOL COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5739347-A | REDUCING AGENTS FOR DECARBONYLATION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5663348-A | REDUCTION OF DIKETONE WITH AMINOALKOXYBORANE COMPLEX TO FORM DIALCOHOL ESTER COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0680484-A1 | OPTICALLY ACTIVE $g(b)-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017079-A1 | OPTICALLY ACTIVE β-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-08-04 | — | — | WO | disclosed |
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066682-A1 | Arylalkylamine vanadium (V) salts for the treatment and/or prevention of Diabetes mellitus | GPR119, ABCC1, INSR | KDM4E 1361/4885ALDH1A1 177/4885GAA 478/4885 |
| US-20130303775-A1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | ADH1C, ADH1A, ADH5 | KDM4E 1985/4885ALDH1A1 250/4885GAA 4030/4885 |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | KDM4E 1046/4885ALDH1A1 4523/4885GAA 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.