Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19891039 | 0.81 | HTT (0.68) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL17465537 | 0.81 | HTT (0.68) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL3067730 | 0.80 | GAA (0.86) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8612093 | 0.79 | HTT (0.66) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL25507531 | 0.78 | HTT (0.64) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL25494263 | 0.78 | HTT (0.64) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL25474912 | 0.78 | TDP1 (0.56) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6068080 | 0.77 | HTT (0.62) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12347759 | 0.76 | LMNA (0.59) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14447512 | 0.75 | TAS2R38 (0.58) | ALDH1A1MEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11571481-B2 | Peptide-linked drug delivery system | CORNELL UNIVERSITY (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220193248-A1 | PEPTIDE-LINKED DRUG DELIVERY SYSTEM | CORNELL UNIVERSITY | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193248-A1 | PEPTIDE-LINKED DRUG DELIVERY SYSTEM | GLS, AGBL2, ATP6V1B1 | HTT 1255/4885ALDH1A1 3364/4885MEN1 2191/4885 |
| US-11571481-B2 | Peptide-linked drug delivery system | GLS, AGBL2, ATP6V1B1 | HTT 1255/4885ALDH1A1 3364/4885MEN1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.