Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.35 |
| ▸ | CA1 | P00915 | 10/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490762 | 0.78 | CA2 (0.56) | CA2CA1CA9CA12PTGS2 | |
| SCHEMBL2451533 | 0.69 | EGFR (0.39) | — | |
| SCHEMBL491028 | 0.68 | HTR6 (0.50) | CA2CA1CA9CA12TDP1 | |
| SCHEMBL2454799 | 0.67 | SCN9A (0.32) | PTGS2 | |
| SCHEMBL491053 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL30687380 | 0.60 | NPC1 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL8023017 | 0.60 | NPC1 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL3967301 | 0.60 | — | — | |
| SCHEMBL27954274 | 0.60 | CA2 (0.65) | CA2CA1CA9CA12PTGS2 | |
| SCHEMBL4575215 | 0.60 | CA2 (0.79) | CA2CA1CA9CA12PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110223540-A1 | GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK COMPANY | 2011-09-15 | — | — | US | disclosed |