Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563018 | 0.84 | CYP17A1 (0.43) | CYP11B1CYP11B2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL421967 | 0.77 | KEAP1 (0.56) | CYP3A4CYP1A2CHRM2CYP2D6CHRM1 | |
| SCHEMBL1424751 | 0.72 | CYP19A1 (0.47) | CYP24A1FAAHMGLLCYP3A4CYP19A1 | |
| SCHEMBL10405171 | 0.71 | CYP24A1 (0.44) | CYP11B1CYP11B2CYP24A1FAAHMGLL | |
| SCHEMBL10405169 | 0.71 | CYP24A1 (0.44) | CYP11B1CYP11B2CYP24A1FAAHMGLL | |
| SCHEMBL30366356 | 0.69 | FAAH (0.44) | CYP24A1FAAHMGLLCYP3A4LMNA | |
| SCHEMBL28098359 | 0.69 | FAAH (0.48) | CYP24A1FAAHMGLLCYP3A4CYP19A1 | |
| SCHEMBL22590608 | 0.69 | CYP19A1 (0.42) | CYP24A1FAAHMGLLLMNACYP19A1 | |
| SCHEMBL11883684 | 0.69 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP24A1CYP3A4LMNA | |
| SCHEMBL5314422 | 0.69 | ALDH1A1 (0.36) | CYP24A1FAAHMGLLLMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011116491-A1 | PREPARATION METHOD FOR NORTROPINE BENZILATE AND ITS SALTS AND INTERMEDIATES USED IN SAID METHOD | 北京世纪迈劲生物科技有限公司 (CN) | 2011-09-29 | — | — | WO | disclosed |
| US-20100048903-A1 | Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds | K.H.S. PHARMA HOLDING GMBH (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20100048903-A1 | Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds | K.H.S. PHARMA HOLDING GMBH (DE) | 2010-02-25 | — | — | US | disclosed |
| WO-2008101728-A1 | METHOD FOR PRODUCING AZONIASPIRONORTROPINE ESTERS AND NORTROPAN-3-ONE COMPOUNDS | K.H.S. PHARMA HOLDING GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |
| US-4855422-A | Process for the preparation of azoniaspironortropanol esters | MADAUS GMBH & CO. (DE) | 1989-08-08 | — | — | US | disclosed |
| US-4549021-A | N-(β-Fluoroethyl)-nortropine | BOEHRINGER INGELHEIM KG (DE) | 1985-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048903-A1 | Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds | THOP1, NTSR1, NTSR2 | CYP11B1 43/4885CYP11B2 29/4885CYP24A1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.