Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453912 | 0.77 | KDM4E (0.42) | ALDH1A1CNR1GPR55CNR2MAPT | |
| SCHEMBL2456915 | 0.77 | NOTUM (0.50) | ALDH1A1CNR1GPR55CNR2MAPT | |
| SCHEMBL9134518 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2453874 | 0.70 | PRMT6 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19CNR1 | |
| SCHEMBL2455752 | 0.68 | MEN1 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2454798 | 0.68 | MAPT (0.49) | ALDH1A1HPGDMAPTMAPK1L3MBTL1 | |
| SCHEMBL2453925 | 0.65 | MEN1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL13818615 | 0.65 | MAPT (0.33) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL17710261 | 0.64 | NOTUM (0.45) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13809576 | 0.63 | PTGS2 (0.49) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958948-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1958948-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | ALDH1A1 3397/4885HPGD 533/4885CYP1A2 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.