SCHEMBL24596643

SCHEMBL24596643

c1ccc2c(c1)-c1cccc3ccc4c(c13)c1c-2cccc1n4-c1nc2ccccc2nc1-c1cccc2c1sc1ccccc12

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PRKDC P78527 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
PARP14 Q460N5 1/20 0.32
HTT P42858 1/20 0.31
PAX8 Q06710 1/20 0.31
CYP1A2 P05177 1/20 0.31
ADK P55263 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24596622 0.94 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL23031030 0.92 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL23030697 0.90 PRKDC (0.34) ALOX5PRKDCPIK3CDPIK3CBHTT
SCHEMBL24117002 0.90 PRMT5 (0.32) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL24117244 0.90 PRMT5 (0.32) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL18877000 0.89 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBPARP14
SCHEMBL21366731 0.89 ALOX5 (0.33) ALOX5
SCHEMBL21366858 0.87 ALOX5 (0.33) ALOX5PRKDCCYP1A2ADK
SCHEMBL21366758 0.85 ALOX5 (0.35) ALOX5PRKDCADK
SCHEMBL24596645 0.85 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 US disclosed
US-20220393116-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed
US-20220216433-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216433-A1 ELECTROLUMINESCENT DEVICE EML4, EMC2, L1CAM ALOX5 4395/4885PRKDC 3716/4885PIK3CD 3921/4885
US-20220393116-A1 ELECTROLUMINESCENT DEVICE L1CAM, MCOLN2, MCOLN1 ALOX5 2816/4885PRKDC 4830/4885PIK3CD 4748/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB ALOX5 1877/4885PRKDC 4272/4885PIK3CD 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.