Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.49 |
| ▸ | HTR1B | P28222 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27099115 | 0.86 | ALDH1A1 (0.68) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL6242131 | 0.85 | ALDH1A1 (0.66) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL6131655 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL9157585 | 0.82 | HTR7 (0.66) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL29244383 | 0.82 | TSHR (0.62) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL1664328 | 0.81 | HPGD (0.73) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL5483044 | 0.81 | PKM (0.64) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL8297234 | 0.81 | HTR1D (0.67) | TSHRNFKB1HTR7HTR1AHTR1D | |
| SCHEMBL29350604 | 0.80 | NPSR1 (1.00) | TSHRHPGDALDH1A1CYP2C9LMNA | |
| SCHEMBL138121 | 0.80 | NPSR1 (1.00) | TSHRHPGDALDH1A1CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075931-A2 | REACTIVE HETEROCYCLIC DERIVATIVES AND METHODS FOR THEIR SYNTHESIS AND USE | BIOSITE INCORPORATED (US) | 2007-07-05 | — | — | WO | disclosed |