SCHEMBL2462987

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2458167	0.80	BTK (0.41)	BTKTLR8CNR1CNR2KMT2A
	SCHEMBL2462773	0.80	BTK (0.39)	BTKTLR8CNR1CNR2KMT2A
	SCHEMBL2578706	0.75	PDE5A (0.41)	BTKTLR8CNR1CNR2KMT2A
	SCHEMBL2461065	0.74	KDM4E (0.40)	MAPTTP53SMN1; SMN2GAATDP1
	SCHEMBL2461306	0.73	IMPDH2 (0.40)	BTKTLR8CNR1CNR2KMT2A
	SCHEMBL2590584	0.73	TUBB4A (0.39)	BTKTLR8KMT2AMEN1PLA2G1B
	SCHEMBL1136128	0.73	CCR8 (0.36)	KMT2AMEN1PLA2G1BATG4BPDE5A
	SCHEMBL28267274	0.71	TLR8 (0.53)	TLR8CNR1CNR2KMT2AMEN1
	SCHEMBL9330248	0.69	TLR8 (0.48)	BTKTLR8CNR1CNR2KMT2A
	SCHEMBL2458247	0.69	ALDH1A1 (0.40)	MAPTTP53SMN1; SMN2GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.