Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373128 | 0.78 | HCAR3 (0.34) | HCAR3HCAR2OPRM1OPRL1GALR3 | |
| SCHEMBL25329372 | 0.65 | ALDH1A1 (0.38) | OPRM1OPRL1GALR3MAPTALDH1A1 | |
| SCHEMBL14939165 | 0.61 | MAPT (0.49) | HCAR3HCAR2OPRM1GALR3MAPT | |
| SCHEMBL4814723 | 0.61 | OPRM1 (0.47) | CCR2OPRM1OPRL1CNR2MEN1 | |
| SCHEMBL17146208 | 0.60 | CCR2 (0.47) | HCAR3HCAR2CCR2OPRM1OPRL1 | |
| SCHEMBL7310701 | 0.59 | PDK2 (0.47) | OPRL1CHRM5 | |
| SCHEMBL696251 | 0.59 | AKR1C3 (0.67) | CCR2OPRM1OPRL1MAPTMEN1 | |
| SCHEMBL15701118 | 0.59 | SLC6A4 (0.51) | CCR2OPRM1OPRL1MAPTNPSR1 | |
| SCHEMBL28650686 | 0.59 | HDAC3 (0.51) | CCR2OPRM1OPRL1NPSR1 | |
| Hydrochloric Acid SCHEMBL4815021 | 0.58 | TACR1 (0.48) | CCR2OPRM1OPRL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119701-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |