Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005294 | 0.97 | ACHE (0.40) | ACHEBCL2L1BADORAI1ORAI2 | |
| SCHEMBL29739004 | 0.87 | SLC22A2 (0.46) | ACHE | |
| Hydrochloric Acid SCHEMBL2463096 | 0.79 | ALDH1A1 (0.55) | RAB9A | |
| Hydrochloric Acid SCHEMBL2465644 | 0.78 | KMT2A (0.64) | ACHENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2264607 | 0.76 | MMP2 (0.37) | ACHEPTPN1 | |
| Hydrochloric Acid SCHEMBL10577155 | 0.75 | ACHE (0.41) | ACHEMAOB | |
| Hydrochloric Acid SCHEMBL14937603 | 0.75 | ACHE (0.44) | ACHENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL598047 | 0.74 | SLC22A2 (0.46) | ACHENPC1RAB9A | |
| SCHEMBL12216504 | 0.73 | MAPT (0.52) | — | |
| SCHEMBL12267700 | 0.72 | ACHE (0.43) | ACHEORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594558-A1 | COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME | KH Neochem Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20130123494-A1 | COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME | KH NEOCHEM CO., LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-8014056-B2 | Display element and method of driving the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2096490-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | Konica Minolta Holdings, Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123494-A1 | COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME | TRPA1, KCNH3, HCN3 | ACHE 518/4885BCL2L1 3713/4885BAD 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.