Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377184 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL8741192 | 0.84 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL6322393 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL3317227 | 0.83 | GAA (0.56) | ALDH1A1SMN1; SMN2LMNAGAABCL9 | |
| SCHEMBL27421509 | 0.81 | ALOX5 (0.60) | ALDH1A1SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL2890042 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL457863 | 0.79 | HSPB1 (0.68) | ALDH1A1SMN1; SMN2LMNAKDM4EDRD2 | |
| SCHEMBL28563483 | 0.79 | GAA (0.51) | ALDH1A1SMN1; SMN2LMNAGAAKDM4E | |
| SCHEMBL5488824 | 0.78 | BCL9 (0.56) | ALDH1A1SMN1; SMN2LMNAGAABCL9 | |
| Methane SCHEMBL11686999 | 0.78 | CES2 (0.60) | ALDH1A1SMN1; SMN2ALOX5LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | The Florida State University Research Foundation, Inc. (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | DDC, NISCH, TST | ALDH1A1 1033/4885SMN1; SMN2 4347/4885ALOX5 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.