Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23137337 | 0.97 | EPHX1 (0.42) | EPHX1SHBGTP53ALDH1A1HSD17B10 | |
| SCHEMBL3870816 | 0.97 | EPHX1 (0.42) | EPHX1SHBGTP53ALDH1A1HSD17B10 | |
| SCHEMBL5575734 | 0.93 | EPHX1 (0.43) | EPHX1SHBGTP53ALDH1A1HSD17B10 | |
| SCHEMBL7631066 | 0.76 | — | — | |
| SCHEMBL3069318 | 0.76 | EPHX1 (0.42) | EPHX1SHBGTP53ALDH1A1HSD17B10 | |
| SCHEMBL23744997 | 0.76 | EPHX1 (0.42) | EPHX1SHBGTP53ALDH1A1HSD17B10 | |
| SCHEMBL13619070 | 0.71 | SHBG (0.56) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL22626479 | 0.71 | EPHX1 (0.44) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL5680409 | 0.71 | — | — | |
| SCHEMBL9064120 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478751-A | Complex salts having high electric conductivity | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | claimed |
| EP-3812358-B1 | METHOD OF MANUFACTURING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC (JP) | 2023-08-23 | — | — | EP | disclosed |
| EP-4212501-A1 | MIXTURE COMPRISING 2-CHLORO-1,3,3,3-TETRAFLUOROPROPENE AND 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC. (JP) | 2023-07-19 | — | — | EP | disclosed |
| EP-3730471-B1 | METHOD FOR REMOVING 2-CHLORO-1,3,3,3-TETRAFLUOROPROPENE AND METHOD FOR PRODUCING 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC (JP) | 2023-03-22 | — | — | EP | disclosed |
| US-11046630-B2 | Method for producing 1-chloro-2,3,3,4,4,5,5-heptafluoro-1-pentene, and composition | AGC Inc. (JP) | 2021-06-29 | — | — | US | disclosed |
| EP-3812358-A1 | METHOD OF MANUFACTURING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC. (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-20210053896-A1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3,4,4,5,5-HEPTAFLUORO-1-PENTENE, AND COMPOSITION | AGC Inc. (JP) | 2021-02-25 | — | — | US | disclosed |
| EP-3330243-B1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3-TRIFLUOROPROPENE | AGC INC (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-10851034-B2 | Method of removing 2-chloro-1,3,3,3-tetrafluoropropene and method of producing 1-chloro-2,3,3,3-tetrafluoropropene | AGC Inc. (JP) | 2020-12-01 | — | — | US | disclosed |
| EP-3395789-B1 | MANUFACTURING METHOD OF 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE | AGC INC (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-2218708-B1 | METHOD FOR PRODUCING CARBONATE COMPOUND | ASAHI GLASS CO LTD (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-8357828-B2 | Processes for producing 1,1-dichloro-2,3,3,3-tetrafluoropropene and 2,3,3,3-tetrafluoropropene | ASAHI GLASS COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20110251442-A1 | PROCESSES FOR PRODUCING 1,1-DICHLORO-2,3,3,3-TETRAFLUOROPROPENE AND 2,3,3,3-TETRAFLUOROPROPENE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2371793-A1 | PROCESSES FOR PRODUCTION OF 1,1-DICHLORO-2,3,3,3-TETRA- FLUOROPROPENE AND 2,3,3,3-TETRAFLUOROPROPENE | Asahi Glass Company Limited (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20100240912-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND | ASAHI GLASS COMPANY, LIMITED | 2010-09-23 | — | — | US | disclosed |
| EP-2218708-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND | Asahi Glass Co., Ltd. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-5055601-A | Epoxidizing fluoroolefin with hypochlorite in basic two phase system containing lipophilic phase transfer catalyst | ASAHI KASEI KOGYO K.K. (JP) | 1991-10-08 | — | — | US | disclosed |
| US-4965379-A | EPOXIDATION OF FLUOROOLEFIN | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| US-4478751-A | Complex salts having high electric conductivity | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0100488-A1 | Fluoroepoxides and a process for production thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251442-A1 | PROCESSES FOR PRODUCING 1,1-DICHLORO-2,3,3,3-TETRAFLUOROPROPENE AND 2,3,3,3-TETRAFLUOROPROPENE | TFDP2, PCTP, HACL2 | CHRM1 2499/4885CHRM3 2184/4885EPHX1 1974/4885 |
| US-11046630-B2 | Method for producing 1-chloro-2,3,3,4,4,5,5-heptafluoro-1-pentene, and composition | HTR3C, CTRB2, PUM1 | CHRM1 35/4885CHRM3 21/4885EPHX1 784/4885 |
| US-20100240912-A1 | METHOD FOR PRODUCING CARBONATE COMPOUND | CA6, FRG1, CA3 | CHRM1 2752/4885CHRM3 1887/4885EPHX1 2663/4885 |
| US-10851034-B2 | Method of removing 2-chloro-1,3,3,3-tetrafluoropropene and method of producing 1-chloro-2,3,3,3-tetrafluoropropene | CPNE4, CCR4, CYP4F2 | CHRM1 1724/4885CHRM3 1305/4885EPHX1 1432/4885 |
| US-20210053896-A1 | METHOD FOR PRODUCING 1-CHLORO-2,3,3,4,4,5,5-HEPTAFLUORO-1-PENTENE, AND COMPOSITION | HTR3C, CTRB2, PUM1 | CHRM1 35/4885CHRM3 21/4885EPHX1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.