SCHEMBL24702670

SCHEMBL24702670

CC(C)c1nc2ccccc2nc1-c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.44
▸ ALDH1A1 P00352 5/20 0.44
▸ RAB9A P51151 5/20 0.44
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ NPC1 O15118 3/20 0.44
▸ AHR P35869 1/20 0.44
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2A6 P11509 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HPRT1 P00492 1/20 0.38
▸ BCHE P06276 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ PGK1 P00558 1/20 0.36
▸ DHFR P00374 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341548 0.82 ALDH1A1 (0.57) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL20932105 0.79 ADORA2A (0.43) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL23874989 0.78 ALOX5 (0.42) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL25900270 0.78 ALDH1A1 (0.41) MAPTALDH1A1CYP1A2CYP2A6TSHR
SCHEMBL19169637 0.77 DHFR (0.50) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL29516865 0.74 KDM4E (0.53) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL12914322 0.74 CYP1A2 (0.49) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL19816494 0.74 KDM4E (0.53) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL24704046 0.73 KDM4E (0.43) MAPTALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL19161268 0.73 ALDH1A1 (0.42) MAPTALDH1A1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 — — US disclosed
US-20220393116-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393116-A1 ELECTROLUMINESCENT DEVICE L1CAM, MCOLN2, MCOLN1 MAPT 1062/4885ALDH1A1 761/4885RAB9A 570/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB MAPT 3576/4885ALDH1A1 442/4885RAB9A 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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