Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179259 | 0.81 | NPC1 (0.41) | — | |
| SCHEMBL22281824 | 0.71 | NPC1 (0.44) | — | |
| SCHEMBL10948259 | 0.69 | BACE1 (0.43) | — | |
| Benzotriazole SCHEMBL28258951 | 0.68 | ALDH1A1 (0.39) | — | |
| SCHEMBL31110437 | 0.68 | QDPR (0.47) | — | |
| SCHEMBL366171 | 0.67 | CLK2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL31110482 | 0.67 | QDPR (0.46) | — | |
| SCHEMBL19640293 | 0.67 | CLK1 (0.34) | — | |
| Benzotriazole SCHEMBL8956 | 0.66 | — | — | |
| Benzotriazole SCHEMBL6088869 | 0.66 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306604-A1 | CYCLOBUTYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306604-A1 | CYCLOBUTYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | TRPV1, SCN7A, TRPA1 | NISCH 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.