Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19317595 | 0.82 | SLC6A4 (0.44) | MAPTPTGER4 | |
| SCHEMBL22225305 | 0.82 | STK39 (0.47) | PPARGL3MBTL1MAPTNPSR1TEAD1 | |
| SCHEMBL14020503 | 0.82 | PPARG (0.51) | PPARGL3MBTL1MAPTTEAD1ALDH1A1 | |
| SCHEMBL12868961 | 0.81 | LTA4H (0.49) | PPARGL3MBTL1MAPTTEAD1PTGER4 | |
| SCHEMBL22888655 | 0.81 | DUT (0.43) | L3MBTL1 | |
| SCHEMBL24726455 | 0.77 | HDAC4 (0.41) | PPARGPTGER4KDM4E | |
| SCHEMBL255035 | 0.73 | PNMT (0.55) | MAPTNPSR1 | |
| SCHEMBL22185405 | 0.73 | PLG (0.41) | AKR1C3AKR1C2 | |
| SCHEMBL9798371 | 0.73 | LTA4H (0.54) | L3MBTL1MAPTNPSR1TEAD1ALDH1A1 | |
| SCHEMBL29623441 | 0.72 | NPSR1 (0.56) | L3MBTL1MAPTNPSR1TEAD1EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |