SCHEMBL2473829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2474850	0.89	NPC1 (0.46)	DHODHMAPTNPC1GABRA5POLB
	SCHEMBL2474038	0.86	MAPT (0.44)	DHODHMAPTMLYCDNPC1GABRA2
	SCHEMBL2470928	0.81	MAPK14 (0.48)	MAPTGABRA5POLBALOX15TSHR
	SCHEMBL2472887	0.81	PTGS1 (0.48)	MAPTNPC1GABRA5KDM4EALDH1A1
	SCHEMBL2471679	0.79	PTGS2 (0.50)	MAPTSMN1; SMN2ALDH1A1LMNAMAPK14
	SCHEMBL2472364	0.78	GABRA5 (0.43)	MAPTNPC1GABRA5MAPK14L3MBTL1
	SCHEMBL4506401	0.72	NPC1 (0.50)	MAPTNPC1CACNA1FCACNA1DCACNA1S
	SCHEMBL2468902	0.72	PTGS1 (0.47)	MAPTNPC1GABRA5POLBTSHR
	SCHEMBL2470833	0.72	L3MBTL1 (0.46)	MAPTNPC1CACNA1FCACNA1DCACNA1S
	SCHEMBL2470836	0.72	MAPK14 (0.48)	MAPTPOLBALOX15TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.