SCHEMBL2474075

SCHEMBL2474075

CC(C)NCCNCCO

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
CNR1 P21554 1/20 0.33
ADRA1A P35348 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ABCC3 O15438 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TOP2B Q02880 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745076 0.86 LMNA (0.32) LMNATDP1KDM4EALDH1A1
SCHEMBL4745112 0.86 LMNA (0.32) LMNATDP1KDM4EALDH1A1
SCHEMBL17766693 0.86 LMNA (0.32) LMNATDP1KDM4EALDH1A1
SCHEMBL4746164 0.86 LMNA (0.32) LMNATDP1KDM4EALDH1A1
SCHEMBL17766691 0.86 LMNA (0.32) LMNATDP1KDM4EALDH1A1
SCHEMBL25554530 0.85 LMNA (0.31) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10617948 0.85 ALDH1A1 (0.37) LMNAKDM4EALDH1A1
SCHEMBL143017 0.83
SCHEMBL22385121 0.81
Hydrochloric Acid SCHEMBL11896951 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012089781-A1 PROCESS FOR REMOVING SULPHUR-CONTAINING CONTAMINANTS FROM A GAS STREAM SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2012-07-05 WO claimed
US-6342169-B1 ABSORPTION OF SALT FORM IN WATER MEDIUM CONTAINING WATER SOLUBLE AMINE; SATURATION; STORAGE STABILITY CANSOLV TECHNOLOGIES, INC. (CA) 2002-01-29 US claimed
EP-0581026-B1 Removal of hydrogen sulfide UNION CARBIDE CHEM PLASTIC (US) 1996-10-23 EP claimed
US-5304361-A Removal of hydrogen sulfide UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-19 US claimed
EP-0581026-A1 Removal of hydrogen sulfide UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-02-02 EP claimed
US-5262139-A Desulfurization by absorption with diamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-11-16 US claimed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP claimed
EP-0548543-A1 Removal of sulfur dioxide from gas streams UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-30 EP claimed
US-5202103-A Using aqueous alkaline calcium oxide slurries UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-04-13 US claimed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-11672818-B2 Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-06-13 US disclosed
US-20230174679-A1 NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2023-06-08 US disclosed
US-20230159532-A1 PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2023-05-25 US disclosed
US-11421044-B2 Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2022-08-23 US disclosed
US-20210346424-A1 NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2021-11-11 US disclosed
US-5262139-A Desulfurization by absorption with diamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-11-16 US disclosed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP disclosed
EP-0548543-A1 Removal of sulfur dioxide from gas streams UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-30 EP disclosed
US-5202103-A Using aqueous alkaline calcium oxide slurries UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-04-13 US disclosed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159532-A1 PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF PTH1R, CALCR, VDR LMNA 1955/4885CNR1 788/4885ADRA1A 1291/4885
US-20230174679-A1 NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO NOS2, NOS3, NOS1 LMNA 2073/4885CNR1 2230/4885ADRA1A 1597/4885
US-11672818-B2 Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto NOS1, NOS2, NOS3 LMNA 3685/4885CNR1 999/4885ADRA1A 393/4885
US-11421044-B2 Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto NOS2, NOS3, NOS1 LMNA 2073/4885CNR1 2230/4885ADRA1A 1597/4885
US-20210346424-A1 NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO NOS1, NOS2, NOS3 LMNA 3685/4885CNR1 999/4885ADRA1A 393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.