SCHEMBL4745112

SCHEMBL4745112

CC(C)NCCNCCNCCNC(C)C

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
ALOX15 P16050 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17766691 1.00 LMNA (0.32) LMNATDP1CA12CA1CA2
SCHEMBL4746164 1.00 LMNA (0.32) LMNATDP1CA12CA1CA2
SCHEMBL17766693 1.00 LMNA (0.32) LMNATDP1CA12CA1CA2
SCHEMBL4745076 1.00 LMNA (0.32) LMNATDP1CA12CA1CA2
SCHEMBL16781965 0.91
SCHEMBL272858 0.89 TDP1 (0.36) LMNATDP1KDM4E
SCHEMBL18551186 0.88 ALDH1A1 (0.35) ALDH1A1
SCHEMBL20733072 0.88 CYP2C19 (0.48) TP53
SCHEMBL19836838 0.88
SCHEMBL14952396 0.88 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914254-B1 Crosslinkers for improving stability of polyurethane foams EVONIK DEGUSSA GMBH (DE) 2017-08-23 EP claimed
EP-1914254-A1 Crosslinkers for improving stability of polyurethane foams Air Products and Chemicals, Inc. (US) 2008-04-23 EP claimed
US-20080090922-A1 Crosslinkers for improving stability of polyurethane foams EVONIK OPERATIONS GMBH (DE) 2008-04-17 US claimed
WO-2025062883-A1 SYSTEM FOR REMOVING NITROGEN OXIDES AND/OR SULFUR OXIDES, METHOD FOR REMOVING NITROGEN OXIDES AND/OR SULFUR OXIDES, SYSTEM FOR SEPARATING AND CAPTURING CARBON DIOXIDE, AND METHOD FOR SEPARATING AND CAPTURING CARBON DIOXIDE 国立大学法人京都工芸繊維大学 2025-03-27 WO disclosed
WO-2023182173-A1 CARBON DIOXIDE ISOLATOR, METHOD FOR ISOLATING OR RECOVERING CARBON DIOXIDE, AND METHOD FOR PRODUCING CARBON DIOXIDE ISOLATOR 公益財団法人地球環境産業技術研究機構 2023-09-28 WO disclosed
US-11584933-B2 RNA interference in ocular indications PHIO PHARMACEUTICALS CORP. (US) 2023-02-21 US disclosed
EP-3390483-B1 ENCAPSULATION PROCTER & GAMBLE (US) 2022-05-18 EP disclosed
EP-3368207-B1 ENCAPSULATION ENCAPSYS LLC (US) 2021-12-01 EP disclosed
US-11001845-B2 Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) PHIO PHARMACEUTICALS CORP. (US) 2021-05-11 US disclosed
US-20210062195-A1 RNA INTERFERENCE IN OCULAR INDICATIONS PHIO PHARMACEUTICALS CORP. (US) 2021-03-04 US disclosed
US-10864167-B2 Encapsulation THE PROCTER & GAMBLE COMPANY (US) 2020-12-15 US disclosed
US-20170067056-A1 RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS RXI PHARMACEUTICALS CORPORATION (US) 2017-03-09 US disclosed
US-20170051290-A1 METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES RXI PHARMACEUTICALS CORPORATION (US) 2017-02-23 US disclosed
US-20160144340-A1 CARBON DIOXIDE SEPARATING MATERIAL, AND METHOD FOR SEPARATION OR RECOVERY OF CARBON DIOXIDE RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH (JP) 2016-05-26 US disclosed
US-8552078-B2 Non-fugitive tertiary amine catalyst and alkylated polyamine crosslinking additives; aging resistance AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-08 US disclosed
US-20110052673-A1 THERAPEUTIC COMPOSITIONS SHIRE HUMAN GENETIC THERAPIES, INC. 2011-03-03 US disclosed
US-20110009641-A1 Amine-containing lipids and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-01-13 US disclosed
WO-2008112636-A1 CHAIN EXTENDERS ALBEMARLE CORPORATION (US) 2008-09-18 WO disclosed
EP-1914254-A1 Crosslinkers for improving stability of polyurethane foams Air Products and Chemicals, Inc. (US) 2008-04-23 EP disclosed
US-20080090922-A1 Crosslinkers for improving stability of polyurethane foams EVONIK OPERATIONS GMBH (DE) 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584933-B2 RNA interference in ocular indications RXRA, RXRB, RXRG LMNA 1015/4885TDP1 3077/4885CA12 4498/4885
US-20110052673-A1 THERAPEUTIC COMPOSITIONS PHOSPHO1, SGMS1, APOB LMNA 536/4885TDP1 3041/4885CA12 1652/4885
US-11001845-B2 Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) SOD1, SOD3, POLRMT LMNA 583/4885TDP1 57/4885CA12 3945/4885
US-20170051290-A1 METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES POLRMT, NSUN3, ELAVL1 LMNA 461/4885TDP1 496/4885CA12 1935/4885
US-20110009641-A1 Amine-containing lipids and uses thereof PHOSPHO1, CHMP4B, SGMS1 LMNA 402/4885TDP1 1468/4885CA12 4058/4885
US-10864167-B2 Encapsulation ACR, MPHOSPH6, ACMSD LMNA 1251/4885TDP1 653/4885CA12 3364/4885
US-20210062195-A1 RNA INTERFERENCE IN OCULAR INDICATIONS RXRA, RXRB, RXRG LMNA 1015/4885TDP1 3077/4885CA12 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.