Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749862 | 0.88 | TDP1 (0.44) | KDM4EPOLBMAPTMEN1KMT2A | |
| SCHEMBL24748614 | 0.85 | CYP1A2 (0.43) | KDM4EPOLBMAPTMEN1KMT2A | |
| SCHEMBL24748979 | 0.85 | KDM4E (0.39) | KDM4ERXFP1MAPTMEN1KMT2A | |
| SCHEMBL24748942 | 0.85 | CA1 (0.43) | KDM4ERXFP1MAPTMEN1KMT2A | |
| SCHEMBL24748581 | 0.72 | ELANE (0.44) | KDM4EMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL31338820 | 0.71 | ELANE (0.41) | KDM4EEGLN2ARMAPTALDH1A1 | |
| SCHEMBL26665772 | 0.71 | KDM4E (0.53) | KDM4EEGLN2ARPOLBRXFP1 | |
| SCHEMBL30816197 | 0.70 | TRPA1 (0.41) | KDM4EEGLN2ARPOLBRXFP1 | |
| SCHEMBL7393 | 0.67 | CA1 (0.57) | POLBRXFP1MAPTALDH1A1TDP1 | |
| SCHEMBL20764570 | 0.66 | PTPN11 (0.59) | POLBRXFP1MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | King Faisal University (SA) | 2024-05-07 | — | — | US | claimed |
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | ADORA2A, ADORA1, ADORA3 | KDM4E 2435/4885EGLN2 3024/4885AR 530/4885 |
| US-11530217-B1 | Antitubercular compounds | MT-CO3, NOS3, MT-ND3 | KDM4E 2009/4885EGLN2 2800/4885AR 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.