Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749862 | 0.91 | TDP1 (0.44) | KDM4EALDH1A1GAATSHRCYP2C9 | |
| SCHEMBL24748979 | 0.88 | KDM4E (0.39) | KDM4EALDH1A1HPGDNPSR1TSHR | |
| SCHEMBL24748614 | 0.88 | CYP1A2 (0.43) | KDM4EALDH1A1HPGDNPSR1TSHR | |
| SCHEMBL24748595 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL30883370 | 0.71 | KDM4E (0.51) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL24748998 | 0.71 | KLF10 (0.41) | CA2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9726568 | 0.71 | HPGD (0.55) | CA1CA2ALDH1A1HPGDGAA | |
| SCHEMBL24750112 | 0.69 | ALOX15 (0.40) | ALDH1A1GAANPSR1LMNAALOX15 | |
| SCHEMBL28103002 | 0.68 | KDM4E (0.49) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL30816117 | 0.68 | RAB9A (0.42) | CA1CA2KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | ADORA2A, ADORA1, ADORA3 | CA1 4108/4885CA2 2959/4885KDM4E 2435/4885 |
| US-11530217-B1 | Antitubercular compounds | MT-CO3, NOS3, MT-ND3 | CA1 4323/4885CA2 1229/4885KDM4E 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.