Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24748942 | 0.91 | CA1 (0.43) | TDP1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL24748979 | 0.91 | KDM4E (0.39) | TDP1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL24748614 | 0.91 | CYP1A2 (0.43) | TDP1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL24748595 | 0.88 | KDM4E (0.38) | TDP1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL27210452 | 0.83 | SRD5A2 (0.44) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL26665761 | 0.70 | KDM4E (0.59) | TDP1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL24749034 | 0.68 | GLA (0.42) | KDM4EMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL1775145 | 0.67 | TDP1 (0.87) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9856924 | 0.65 | ALDH1A1 (0.65) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| 4-Methylbenzoic Acid Methyl Ester SCHEMBL137891 | 0.65 | TDP1 (1.00) | TDP1MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
| US-11530217-B1 | Antitubercular compounds | King Faisal University (SA) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | ADORA2A, ADORA1, ADORA3 | TDP1 1687/4885KDM4E 2435/4885MAPT 3233/4885 |
| US-11530217-B1 | Antitubercular compounds | MT-CO3, NOS3, MT-ND3 | TDP1 4120/4885KDM4E 2009/4885MAPT 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.