SCHEMBL2480477

SCHEMBL2480477

CC1=Cc2c(Cl)cccc2[CH]1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
PARP1 P09874 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29174107 0.76 CYP2A6 (0.35) ALDH1A1CYP1A2CYP2A6TSHR
SCHEMBL7628753 0.71 CA2 (0.40) ALDH1A1TSHR
SCHEMBL28408727 0.70 CA2 (0.35) ALDH1A1TSHR
SCHEMBL6652271 0.69 HTR7 (0.35) ALDH1A1CYP1A2CYP2A6TSHRNPC1
SCHEMBL28475616 0.69 PDCD1 (0.35) ALDH1A1CYP2A6
SCHEMBL20548534 0.68 PDCD1 (0.38) ALDH1A1CYP1A2CYP2A6LMNATSHR
SCHEMBL8155308 0.67 LMNA (0.36) LMNA
SCHEMBL60946 0.66 ACHE (0.40) CYP1A2LMNATSHR
SCHEMBL15864044 0.65 ADORA2A (0.35) ALDH1A1CYP1A2LMNANPC1RAB9A
SCHEMBL22499662 0.64 ACHE (0.38) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963347-B1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2011-10-19 EP claimed
EP-1963347-B1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2011-10-19 EP disclosed