Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | STAMBP | O95630 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617215 | 0.85 | CSF1R (0.46) | TRPV1EPHX2AURKAPDPK1RPS6KB1 | |
| SCHEMBL619784 | 0.78 | TRPV1 (0.53) | TRPV1KLKB1 | |
| SCHEMBL617313 | 0.77 | ENPP2 (0.46) | TRPV1CSF1RFLT4PDGFRAFLT3 | |
| SCHEMBL616887 | 0.76 | CSF1R (0.47) | TRPV1AURKARPS6KB1AURKBCSF1R | |
| SCHEMBL250792 | 0.76 | TRPV1 (0.46) | TRPV1EPHX2AURKAPDPK1RPS6KB1 | |
| SCHEMBL619224 | 0.76 | TRPV1 (0.43) | TRPV1CSF1RFLT4PDGFRAFLT3 | |
| SCHEMBL253706 | 0.76 | MLYCD (0.58) | TRPV1PSMD14STAMBPCYP3A4CYP2D6 | |
| SCHEMBL252287 | 0.75 | STAMBP (0.51) | PSMD14STAMBPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL253234 | 0.75 | PSMD14 (0.50) | PSMD14STAMBPCYP3A4CYP2C19 | |
| SCHEMBL248207 | 0.75 | CSF1R (0.43) | TRPV1AURKAPDPK1RPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |