Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAMBP | O95630 | 4/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.51 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617276 | 0.83 | HTT (0.50) | SUCNR1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL252709 | 0.79 | STAMBP (0.55) | STAMBPPSMD14COPS5NAMPT | |
| SCHEMBL253706 | 0.79 | MLYCD (0.58) | STAMBPPSMD14COPS5HPGDNAMPT | |
| SCHEMBL253871 | 0.76 | HPGDS (0.60) | STAMBPPSMD14COPS5DYRK1BNAMPT | |
| SCHEMBL253234 | 0.76 | PSMD14 (0.50) | STAMBPPSMD14COPS5ALDH1A1MAPT | |
| SCHEMBL248208 | 0.75 | TRPV1 (0.47) | STAMBPPSMD14CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL617436 | 0.74 | PDPK1 (0.44) | SUCNR1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL253124 | 0.73 | STAMBP (0.44) | STAMBPPSMD14COPS5NAMPT | |
| SCHEMBL5697540 | 0.71 | PSMD14 (0.54) | STAMBPPSMD14COPS5HPGDHTT | |
| SCHEMBL255348 | 0.71 | NAMPT (0.52) | STAMBPPSMD14COPS5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |