Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.58 |
| ▸ | STAMBP | O95630 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13491609 | 0.83 | MLYCD (0.62) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL247656 | 0.83 | LMNA (0.54) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL247884 | 0.81 | LMNA (0.52) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL616941 | 0.81 | DHFR (0.56) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL619841 | 0.80 | LMNA (0.51) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL5697540 | 0.80 | PSMD14 (0.54) | PSMD14STAMBPCYP3A4MAPK14ROCK2 | |
| SCHEMBL252287 | 0.79 | STAMBP (0.51) | PSMD14STAMBPCYP3A4CYP2C19CYP2C9 | |
| SCHEMBL619692 | 0.79 | RIPK1 (0.51) | MLYCDCYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL253234 | 0.78 | PSMD14 (0.50) | PSMD14STAMBPCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL1568282 | 0.78 | MLYCD (0.74) | MLYCDCYP3A4CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |
| EP-2401275-B1 | NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY | RESPIRATORIUS AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |