Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 3/20 | 0.50 |
| ▸ | STAMBP | O95630 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619180 | 0.85 | HCRTR1 (0.44) | LMNAHTTMAPK1GFERL3MBTL1 | |
| SCHEMBL253124 | 0.80 | STAMBP (0.44) | PSMD14STAMBPMAPK1COPS5 | |
| SCHEMBL253706 | 0.78 | MLYCD (0.58) | PSMD14STAMBPLMNACYP1A2CYP3A4 | |
| SCHEMBL252287 | 0.76 | STAMBP (0.51) | PSMD14STAMBPLMNAHTTALDH1A1 | |
| SCHEMBL253233 | 0.75 | SYK (0.40) | LRRK2 | |
| SCHEMBL252709 | 0.75 | STAMBP (0.55) | PSMD14STAMBPMAPK1TSHRCOPS5 | |
| SCHEMBL248208 | 0.75 | TRPV1 (0.47) | PSMD14STAMBPCYP3A4CYP2C19 | |
| SCHEMBL249951 | 0.72 | CTSS (0.48) | LMNALRRK2 | |
| SCHEMBL5697540 | 0.71 | PSMD14 (0.54) | PSMD14STAMBPLMNAHTTSMN1; SMN2 | |
| SCHEMBL18539645 | 0.70 | STAMBP (0.74) | PSMD14STAMBPLMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |