Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485210 | 0.78 | KMT2A (0.33) | — | |
| SCHEMBL467489 | 0.76 | PIM1 (0.36) | — | |
| SCHEMBL2482791 | 0.74 | CASP1 (0.34) | — | |
| SCHEMBL5572047 | 0.70 | HSD11B1 (0.35) | — | |
| SCHEMBL2477477 | 0.70 | NPSR1 (0.43) | — | |
| SCHEMBL169776 | 0.61 | ADRB1 (0.53) | GPR119 | |
| SCHEMBL21689842 | 0.59 | ADRB1 (0.38) | — | |
| SCHEMBL3436329 | 0.58 | SLC18A3 (0.59) | — | |
| SCHEMBL13034556 | 0.58 | KDM4E (0.65) | — | |
| SCHEMBL356595 | 0.58 | GPR119 (0.49) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376494-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVES | MSD K.K. (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010067888-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-06-17 | — | — | WO | disclosed |