SCHEMBL248338

SCHEMBL248338

C=CC(=O)OOC(=O)C(=O)OC(=O)C=C.CCC(CO)(CO)CO

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
THRB P10828 1/20 0.41
TSHR P16473 5/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18107065 0.81 ALDH1A1 (0.50) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL28821613 0.80 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL7986937 0.78 ALDH1A1 (0.47) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL10734344 0.76 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Methyl Ester SCHEMBL31437539 0.75 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Methyl Ester SCHEMBL4817884 0.75 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL7163801 0.74 ALDH1A1 (0.60) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL11105086 0.74 ALDH1A1 (0.60) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL248457 0.73 ALDH1A1 (0.33) ALDH1A1THRBTSHR
SCHEMBL5583873 0.73 ALDH1A1 (0.75) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902127-B Composition for caring for and/or making up keratin materials 莱雅公司 2023-10-03 CN disclosed
CN-107921289-B Water-in-oil emulsion comprising microcapsules encapsulating an oily dispersion of at least one reflecting agent for caring for and/or making up keratin materials 莱雅公司 2023-09-22 CN disclosed
CN-116529328-A Method for preparing film and composition therefor 美国陶氏有机硅公司 2023-08-01 CN disclosed
US-8217388-B2 Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY COMPANY, LTD. (JP) 2012-07-10 US disclosed
US-20120100089-A1 COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD L'OREAL (FR) 2012-04-26 US disclosed
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2012-03-15 US disclosed
US-20120003167-A1 COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL L'OREAL (FR) 2012-01-05 US disclosed
US-20100301377-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW TORAY CO., LTD. (JP) 2010-12-02 US disclosed
EP-2061840-B1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO LTD (JP) 2010-01-06 EP disclosed
EP-2061840-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2009-05-27 EP disclosed
US-7488492-B2 Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product DOW CORNING TORAY COMPANY, LTD. (JP) 2009-02-10 US disclosed
WO-2008023537-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD (JP) 2008-02-28 WO disclosed
EP-1448154-B1 COSMETIC RAW MATERIAL, COSMETIC PRODUCT, AND METHOD FOR MANUFACTURING A COSMETIC PRODUCT DOW CORNING TORAY CO LTD (JP) 2007-09-19 EP disclosed
US-20050008597-A1 Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product DOW TORAY CO., LTD. (JP) 2005-01-13 US disclosed
WO-2004076560-A1 THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-09-10 WO disclosed
WO-2004076547-A1 INORGANIC-POWDER TREATMENT AGENT, INORGANIC POWDER TREATED WITH THE SAME, AND THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-09-10 WO disclosed
EP-1448154-A2 COSMETIC RAW MATERIAL, COSMETIC PRODUCT, AND METHOD FOR MANUFACTURING A COSMETIC PRODUCT Dow Corning Toray Silicone Company, Ltd. (JP) 2004-08-25 EP disclosed
WO-2003045337-A2 COSMETIC RAW MATERIAL, COSMETIC PRODUCT, AND METHOD FOR MANUFACTURING A COSMETIC PRODUCT DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-06-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120003167-A1 COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL QSOX1, RXRB, PRXL2A ALDH1A1 2479/4885TP53 2316/4885CYP3A4 2783/4885
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD PLOD3, ALOX15, ELOVL1 ALDH1A1 3221/4885TP53 1897/4885CYP3A4 4547/4885
US-20050008597-A1 Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product CUTA, CD40LG, FSCN1 ALDH1A1 2417/4885TP53 984/4885CYP3A4 4216/4885
US-20120100089-A1 COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD KRT18, TERB1, VIM ALDH1A1 3581/4885TP53 139/4885CYP3A4 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.