Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388061 | 1.00 | ALDH1A1 (0.67) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL26135477 | 1.00 | ALDH1A1 (0.67) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL3384739 | 1.00 | ALDH1A1 (0.67) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL12086406 | 1.00 | ALDH1A1 (0.67) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL15987982 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL116765 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL943408 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL4582819 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL23196491 | 0.91 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL888164 | 0.91 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3817575-B1 | SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY | SYMRISE AG (DE) | 2025-10-15 | — | — | EP | claimed |
| EP-4583718-A1 | FLAVONOID COMPOSITIONS AND USES THEREOF | Firmenich SA (CH) | 2025-07-16 | — | — | EP | claimed |
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | claimed |
| US-20250176599-A1 | FLAVOR COMPOSITION AND FOOD AND BEVERAGE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2025-06-05 | — | — | US | claimed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | claimed |
| EP-4251122-B1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2025-03-12 | — | — | EP | claimed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | claimed |
| WO-2007022056-A2 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-22 | — | — | WO | claimed |
| WO-2007004740-A1 | VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-01-11 | — | — | WO | claimed |
| WO-2006137556-A1 | FLAVOR AND FRAGRANCE COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-12-28 | — | — | WO | claimed |
| WO-2006130710-A1 | TOPICAL WARMING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2006-12-07 | — | — | WO | claimed |
| EP-1689256-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | Takasago International Corporation (JP) | 2006-08-16 | — | — | EP | claimed |
| WO-2005115325-A1 | MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-12-08 | — | — | WO | claimed |
| US-6956139-B2 | (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-10-18 | — | — | US | claimed |
| WO-2005048743-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-02 | — | — | WO | claimed |
| US-6899901-B2 | Sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-05-31 | — | — | US | claimed |
| US-20020198412-A1 | (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate | GREEN CARTER B (US) | 2002-12-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | ALDH1A1 2893/4885LMNA 4817/4885KDM4E 4202/4885 |
| US-20020198412-A1 | (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate | TAS1R1, TAS2R1, TAS1R3 | ALDH1A1 76/4885LMNA 3297/4885KDM4E 2626/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | ALDH1A1 811/4885LMNA 3005/4885KDM4E 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.