Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GGT1 | P19440 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997189 | 1.00 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| Benzene SCHEMBL3150461 | 0.98 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| Naphthalene SCHEMBL3155078 | 0.95 | PTGS2 (0.47) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL4328045 | 0.89 | HSD17B10 (0.65) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL609102 | 0.84 | CXCL8 (0.40) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL11589528 | 0.84 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL68677 | 0.84 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL30850062 | 0.84 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL10924111 | 0.82 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL3628841 | 0.82 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820200-A | Heterobivalent compound taking piperidinoindenone-salicylic acid as parent, and preparation method and application thereof | 合肥工业大学 | 2024-04-05 | — | — | CN | claimed |
| CN-102297924-B | High performance liquid chromatography method for analyzing impurity content of ortho-tolylacetic acid and 2-chloromethyl phenylacetic acid in 3-isochromanone | SHANGHAI NO 4 REAGENT & H V CHEMICAL CO LTD | 2013-10-30 | — | — | CN | claimed |
| CN-102297924-A | High performance liquid chromatography method for analyzing impurity content of ortho-tolylacetic acid and 2-chloromethyl phenylacetic acid in 3-isochromanone | — | 2011-12-28 | — | — | CN | claimed |
| CN-1303079-C | Process for the preparation of 3-isochromanone | SYNGENTA LTD (GB) | 2007-03-07 | — | — | CN | claimed |
| CN-1653058-A | Process for the preparation of 3-isochromanone | SYNGENTA LTD (GB) | 2005-08-10 | — | — | CN | claimed |
| CN-1102590-C | Process for preparing 3-isochromanone | ZENECA LTD (GB) | 2003-03-05 | — | — | CN | claimed |
| CN-1222150-A | Process for preparing 3-isochromanone | ZENECA LTD (GB) | 1999-07-07 | — | — | CN | claimed |
| EP-4323330-B1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE SALCAPROZIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | NAVINTA III INC (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12454506-B2 | Benzoate derivatives | ZHEJIANG YUEJIA PHARMACEUTICALS CO., LTD (CN) | 2025-10-28 | — | — | US | disclosed |
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| US-20250229198-A1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) | 2025-07-17 | — | — | US | disclosed |
| CN-120117987-A | Arylalkanoic acid phloroglucinol ester compound, preparation method and application thereof | 南华大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119874493-A | Novel method for synthesizing alpha, beta-unsaturated ketone | 广西大学 | 2025-04-25 | — | — | CN | disclosed |
| US-4264771-A | Alkylation of substituted oxazolinone-(5) compounds | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| US-4255336-A | Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01 | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0003274-A1 | o-Substituted (+)-cyanidan-3-ol derivatives, method for their preparation, as well as pharmaceutical compositions containing these compounds and their preparation | Zyma SA (CH) | 1979-08-08 | — | — | EP | disclosed |
| US-4024160-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
| US-3993661-A | Quinone methide photograhpic reagent precursors | POLAROID CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
| US-3932466-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932480-A | PHOTOGRAPHY | POLAROID CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454506-B2 | Benzoate derivatives | NFKBIA, NFKB2, NFKB1 | PTGS2 74/4885KDM4E 522/4885HSD17B10 445/4885 |
| US-20250229198-A1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | SCO2, SOD3, SLC39A3 | PTGS2 2129/4885KDM4E 4827/4885HSD17B10 3211/4885 |
| US-20250243177-A1 | sGC STIMULATORS | GUCY1A1, PTGIS, GUCY1B1 | PTGS2 20/4885KDM4E 2445/4885HSD17B10 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.