SCHEMBL249073

SCHEMBL249073

Fc1cc[c]c2ccccc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
HPRT1 P00492 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386458 0.84 GPR84 (0.31)
SCHEMBL152508 0.75 CYP1A2 (0.33) CYP1A2
SCHEMBL67474 0.73 CYP1A2 (0.50) CYP1A2
SCHEMBL249412 0.73 ALDH1A1 (0.43) CYP1A2HPRT1
SCHEMBL2333542 0.73 ALDH1A1 (0.43) CYP1A2HPRT1
SCHEMBL5747398 0.73 CES2 (0.34)
SCHEMBL5746771 0.73 CA3 (0.33)
SCHEMBL50091 0.71 IDO1 (0.48) CYP1A2
SCHEMBL18394230 0.71 FFAR1 (0.31)
SCHEMBL15452915 0.71 CYP1A2 (0.31) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773586-B Poly (fluorobenzene ester) polymer material and synthetic method thereof 西安交通大学 2024-06-14 CN claimed
WO-2024027947-A1 ANTICANCER AGENTS BASED ON CYCLOPENTENONES UNIVERSITY OF CRETE (GR) 2024-02-08 WO claimed
EP-4316476-A1 ANTICANCER AGENTS BASED ON CYCLOPENTENONES University of Crete (GR) 2024-02-07 EP claimed
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION FIBROGEN, INC. 2024-01-04 US claimed
EP-4204400-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION Fibrogen, Inc. (US) 2023-07-05 EP claimed
CN-116348450-A Compounds, compositions and methods for histone lysine demethylase inhibition 菲布罗根有限公司 2023-06-27 CN claimed
US-11667644-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2023-06-06 US claimed
US-20230115208-A1 RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF TUBERCULOSIS QURETECH BIO AB (SE) 2023-04-13 US claimed
CN-114773586-A Poly (fluorophenyl ester) polymer material and synthesis method thereof 西安交通大学 2022-07-22 CN claimed
US-RE48841-E1 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2021-12-07 US claimed
US-5866549-A MACROLIDE ANTIBIOTICS ABBOTT LABORATORIES (US) 1999-02-02 US claimed
US-5863924-A Aryl pyrimidine derivatives SYNTEX (U.S.A.) INC. (US) 1999-01-26 US claimed
US-5804348-A COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY EASTMAN KODAK COMPANY (US) 1998-09-08 US claimed
US-5750305-A Poly (2-(sulfonamidomethylene)-2-cyanoacetamido)phenyl acrylate! charge-control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 1998-05-12 US claimed
WO-1998009978-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY ABBOTT LABORATORIES (US) 1998-03-12 WO claimed
WO-1997044326-A1 ARYL PYRIMIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1997-11-27 WO claimed
US-5559154-A Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists OREGON STATE BOARD OF HIGHER EDUCATION 1996-09-24 US claimed
EP-0708085-A2 Antiviral ethers of aspartate protease substrate isosteres CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
US-5262568-A Neuroprotective compounds, high binding affinity for phencyclidine, nervous system disorders STATE OF OREGON (US) 1993-11-16 US claimed
US-4112219-A Acyl derivatives of antibiotic BM123γ AMERICAN CYANAMID COMPANY (US) 1978-09-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230115208-A1 RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF TUBERCULOSIS IL17A, TBCB, TBC1D15 CYP1A2 247/4885HPRT1 715/4885
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION KDM5C, KDM5B, KDM5A CYP1A2 3777/4885HPRT1 2594/4885
US-11667644-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators HCRTR2, HCRTR1, OXTR CYP1A2 2758/4885HPRT1 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.